オオノ　ミチヤ   OHNO MICHIYA   大野　道也    所属   朝日大学  歯学部 総合医科学講座 内科学（朝日大学病院）    職種   教授
言語種別	英語
発行・発表の年月	2018/09
形態種別	記事・総説・解説・論説等（学術雑誌）
査読	査読あり
標題	The pathophysiology of chronic cardiorenal disease based on central hemodynamics (Revies Article)
執筆形態	単著
掲載誌名	J Cardiovasc Med Cardiol
掲載区分	国外
出版社・発行元	Peertechz
巻・号・頁	5(3),pp.27-35
総ページ数	9
著者・共著者	Michiya Ohno
概要	As patients with chronic kidney disease (CKD) and chronic heart failure (CHF) increase, there is concern about a future heart failure pandemic. Deterioration of renal function is an independent prognostic factor for CHF after decongestion. Interactions between renal disease and cardiac disease are increasing, including nephrosclerosis and heart failure with preserved ejection fraction (HFpEF), which are both derived from augmentation of central pulse pressure by age-related arterial stiffening. Thus, it is necessary to treat multiple underlying diseases of cardiorenal syndrome simultaneously. However, an effective therapeutic strategy for HFpEF has not been established. This review reconsiders the pathophysiology of chronic cardiorenal disease related to arterial stiffening from the viewpoint of central hemodynamics and explores treatment options.