イワイ　コウメイ   IWAI KOMEI   岩井　浩明    所属   朝日大学  歯学部 口腔感染医療学講座 社会口腔保健学    朝日大学  大学院 歯学研究科    職種   講師
言語種別	英語
発行・発表の年月	2022/07
形態種別	研究論文（学術雑誌）
査読	査読あり
標題	Association between dental caries and Helicobacter pylori infection in Japanese adults: A cross-sectional study
執筆形態	共著
掲載誌名	PLOS ONE
掲載区分	国外
巻・号・頁	17(7),pp.e0271459
担当区分	筆頭著者
著者・共著者	◎Komei Iwai, Tetsuji Azuma, Takatoshi Yonenaga, Kazutoshi Watanabe, Akihiro Obora, Fumiko Deguchi, Takao Kojima, Takaaki Tomofuji
概要	In this cross-sectional study, we examined whether H. pylori infection in blood were associated with dental caries in Japanese adults. The participants were 752 individuals (513 males and 239 females, mean age 53.8 years) who underwent both H. pylori testing (H. pylori antibody test and pepsinogen test) and dental checkups at the Asahi University Hospital Human Health Center between April 2018 and March 2019. In our study, 83 participants (11%) were determined to be infected with H. pylori in the blood. The logistic analysis showed that presence of H. pylori infection in blood was positively associated with those with decayed teeth (OR, 5.656; 95% CI, 3.374 to 9.479). The results indicate that H. pylori infection in blood were associated with decayed teeth. Untreated dental caries may have an impact on systemic H. pylori infection.