イワイ　コウメイ   IWAI KOMEI   岩井　浩明    所属   朝日大学  歯学部 口腔感染医療学講座 社会口腔保健学    朝日大学  大学院 歯学研究科    職種   講師
言語種別	英語
発行・発表の年月	2026/04
形態種別	研究論文
査読	査読あり
標題	Nonalcoholic fatty liver disease assessed by multiple tools are correlated to periodontal conditions
執筆形態	共著
掲載誌名	Scientific Reports
掲載区分	国外
巻・号・頁	16,pp.11589
著者・共著者	◎Takatoshi Hiroshimaya, Komei Iwai, Marika Marutani, Tetsuji Azuma, Takatoshi Yonenaga, Koichiro Tabata, Kazutoshi Watanabe, Fumiko Deguchi, Akihiro Obora, Takao Kojima, Takaaki Tomofuji, Naofumi Tamaki
概要	This study aimed to clarify the relationship between periodontitis and non-alcoholic fatty liver disease (NAFLD). A survey was conducted with 2,453 participants who visited the dental clinic at the Asahi University Hospital. The relationship between periodontitis and the cutoff values of three NAFLD assessment tools by logistic regression analyses indicated that PPD ≥ 6 mm was significantly associated with NFS > 0.675 (OR = 4.11, 95%CI:1.06–15.99) and with FLI ≥ 60 (OR = 1.76, 95%CI:1.12–2.76). The participants with BOP positive indicated a significant association between PPD ≥ 6 mm and FLI ≥ 60 (OR = 1.68, 95%CI:1.05–2.70). However, no association was found in participants without BOP. These results suggest that periodontal inflammation is associated with NAFLD, as assessed using the FLI.