イワイ　コウメイ   IWAI KOMEI   岩井　浩明    所属   朝日大学  歯学部 口腔感染医療学講座 社会口腔保健学    朝日大学  大学院 歯学研究科    職種   講師
言語種別	英語
発行・発表の年月	2018/01
形態種別	研究論文（学術雑誌）
査読	査読あり
標題	Association between α-Klotho and deep white matter lesions in the brain: A pilot case control study using brain MRI
執筆形態	共著
掲載誌名	Journal of Alzheimer's Disease
掲載区分	国外
巻・号・頁	61(1),pp.145-155
著者・共著者	◎Nagato Kuriyama, Etsuko Ozaki, Toshiki Mizuno, Masafumi Ihara, Shigeto Mizuno, Teruhide Koyama, Daisuke Matsui, Isao Watanabe, Kentaro Akazawa, Kazuo Takeda, Akihiro Takada, Masaaki Inaba, Shinsuke Yamada, Koka Motoyama, Wakiko Takeshita, Komei Iwai, Kanae Hashiguchi, Daiki Kobayashi, Masaki Kondo, Aiko Tamura, Kei Yamada, Masanori Nakagawa, Yoshiyuki Watanabe
概要	Association between α-Klotho and deep white mateer lesions in the brain: A pilot case control study using brain MRI. A reduced blood α-Klotho level was correlated with grading of cerebral DWMLs and was accompanied by congnitive decline as an independent risk factor. The α-Klotho level may serve as a useful clinical index of vascular congnitive impairment.