カサイ タダカツ   KASAI TADAKATSU
  笠井 唯克
   所属   朝日大学  歯学部 口腔病態医療学講座 口腔外科学
   朝日大学  大学院 歯学研究科
   職種   准教授
言語種別 日本語
発行・発表の年月 2019/05
形態種別 研究論文(学術雑誌)
標題 Osteogenesis with non-sintered porous carbonate apatite
執筆形態 共著
掲載誌名 International Journal of Oral & Maxilloffacial Surgery
掲載区分国内
巻・号・頁 48,290頁
著者・共著者 T. Kasai, K. Watanabe, Y. Doi, S. Sumitomo
概要 Our purpose was to develop an ideal biomaterial consisting of non-sintered porous CA for bone substitution and to confirm that this material was replaced with bone.
Bone formation was observed at 2 weeks and later. This suggests that the non-sintered porous CA that was precultured with bone marrow cells has the ability to induce bone formation in non-calcified tissues. TRAP staining was used to observe resorption of the sample due to osteoclasts. A TRAP-positive reaction was preferentially observed close to the newly formed bone site. However, it was also slightly visible apart from the area of the bone formation site at 8 weeks.Non-sintered porous CA has the ability to induce bone formation.
ISSN 0901-5027