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ナガナワ コウスケ
NAGANAWA KOSUKE
長縄 鋼亮 所属 朝日大学 歯学部 口腔病態医療学講座 口腔外科学 朝日大学 大学院 歯学研究科 職種 講師 |
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| 言語種別 | 日本語 |
| 発行・発表の年月 | 2015 |
| 形態種別 | 研究論文（学術雑誌） |
| 標題 | Producing capabilities of interferon-gamma and interleukin-10 in peripheral blood from oral squamous cell careinoma patients: the prognostic significance |
| 執筆形態 | 分担執筆 |
| 掲載誌名 | Open Dent J |
| 掲載区分 | 国外 |
| 巻・号・頁 | 9,120-124頁 |
| 担当範囲 | 実験、執筆 |
| 著者・共著者 | Naganawa K,Takayama E,Adachi M,Mitsudo K,Iida M,Kamiya-Mizuno M,Kawaki H,Ichinose M,Motohashi M,Muramatsu Y,Tohnai I,Sumitomo S,Shikimori M,Kondoh N |
| 概要 | In order to evaluate the Th1 and Th2 responses of Oral Squamous Cell Carcinoma patients, We investigated the cytokine producing capability of peripheral blood,and compared it with clinicopathological appearances of OSCC patients.The production of a Th1-type cytokine,interferon(IFN)-γ,from lipopolysaccharide -stimulated PB correlated positively with the frequency of lymph node metastasis. We also investigated the production of a The2-type cytokine,IL-10,however,no significant correlation was observed with the clinicopathological appearances.Our resuluts suggested that the IFN-γ producing capability was specifically regulated and dependent on the regional metastatic potencies of OSSCCs |