アズマ　テツジ   AZUMA TETSUJI   東　哲司    所属   朝日大学  歯学部 口腔感染医療学講座 社会口腔保健学    朝日大学  大学院 歯学研究科    職種   准教授
言語種別	英語
発行・発表の年月	2019/05
形態種別	研究論文（学術雑誌）
標題	Serum microRNAs and chronic periodontitis: A case-control study
執筆形態	共著
掲載誌名	Arch Oral Biol
掲載区分	国外
巻・号・頁	101,pp.57-63
著者・共著者	Yoneda T,Tomofuji T,Ekuni D,Azuma T,Maruyama T,Fujimori K,Sugiura Y,Morita M
概要	An association is present between periodontitis and rates of expression of certain microRNAs (miRNAs) in periodontal tissue. However, the association between periodontitis and miRNA levels in human serum is unknown. We performed a case-control study in patients with chronic periodontitis to investigate serum miRNA levels. Real-time PCR showed that hsa-miR-664a-3p, hsa-miR-501-5p, and hsa-miR-21-3p were higher in the periodontitis group than the control group (p < 0.05). Hsa-miR-664a-3p, hsa-miR-501-5p, and hsa-miR-21-3p are candidate serum biomarkers for chronic periodontitis.
ISSN	0003-9969
PMID	30889506