ムカイ エリコ   MUKAI ERIKO
  向井 理英子
   所属   朝日大学  歯学部 総合医科学講座 内科学(朝日大学病院)
   職種   講師
言語種別 英語
発行・発表の年月 2018
形態種別 研究論文(学術雑誌)
標題 A review of the mechanism and prophylaxis of acetyl salicylic acid-lnduced injury of the small intestine
執筆形態 共著
掲載誌名 FREE RADICAL RESEARCH
掲載区分国外
出版社・発行元 実験補助
担当範囲 実験補助
著者・共著者 Osamu Handa,Shun Takayama,Rieko Mukai,Yosuke Suyama,Atsushi Majima,Akihumi Fukul,Tatsushi Omatsu and Yuji Naito
概要 we found that aspirin significantly increased epithelial cell apoptosis and epithelial permeability.And we investigated the role of intestinal mucus on aspirin-induced mucosal damage using an in vivo model,and found that mucus prevented a high concentration of aspirin-induced mucosal damage.The investigation of chronic users of aspirin revealed that mucus-increasing therapy might be useful for preventing aspirin-induced small intestinal mucosal injury