イワセ　ヨウコ   IWASE YOKO   岩瀬　陽子    所属   朝日大学  歯学部 口腔病態医療学講座 障害者歯科学    朝日大学  大学院 歯学研究科    職種   教授
言語種別	日本語
発行・発表の年月	2019/02
形態種別	研究論文（学術雑誌）
標題	Repeated human deciduous tooth-derived dental pulp cell reprogramming factor transfection yields multipotent intermediate cells with enhanced iPS cell formation capability
執筆形態	共著
掲載誌名	Sci Rep
掲載区分	国外
担当範囲	サンプル採取、細胞培養
著者・共著者	Soda M, Saitoh I, Murakami T, Inada E, Iwase Y, Noguchi H, Shibasaki S, Kurosawa M, Sawami T,Terunuma M, Kubota N, Terao Y, Ohshima H, Hayasaki H, Sato M
概要	We hypothesised that hTSCs, being partially reprogrammed in a state just prior to iPSC transition, could be isolated from any terminally differentiated cell type through transient reprogramming factor overexpression. Our findings suggest that the reverse phenomenon can also occur upon repeated introduction of reprogramming factors into differentiated cells such as HDDPCs and fibroblasts.