タツミ　ジュンイチ   TATSUMI JUNICHI   辰巳　順一    所属   朝日大学  歯学部 口腔感染医療学講座 歯周病学    朝日大学  大学院 歯学研究科    職種   教授
発表年月日	2024/11/04
発表テーマ	Correlation between MMP/TIMP expression in gingival crevicular fluid and clinical parameters in the classification (2017) of periodontal disease.
会議名	The 110th Annual Meeting of the American Academy of Periodontology
主催者	American Academy of Periodontology
学会区分	国際学会
発表形式	ポスター
単独共同区分	共同
国名	アメリカ合衆国
開催地名	San Diego, CA, USA
開催期間	2024/10/31～2024/11/03
発表者・共同発表者	Shimizu Y, Morinaga H, Sato T, Ikami H, Nagase H, Kashimata M, Tatsumi J
概要	GCF contains bioactive substance such as tissue-destructive factors and has attracted attention as one of the diagnostic materials. In this study aims to assess the correlation between GCF MMP/TIMP expression etc,. The expression of MMP-8 and -9 increased after Stage III and IV and Grade B and C, while the expression of TIMP-1 and -2 showed a decreasing trend with increasing stage severity and decreased after Grade B and C. Periodontitis triggers elevated GCF volume, disrupting MMP/TIMP balance, leading to tissue destruction and compromised homeostasis. Evaluating GCF parameters could serve as an objective measure in the classification (2017) of periodontal disease.,