ヤスオ　トシアキ   YASUO TOSHIAKI   安尾　敏明    所属   朝日大学  歯学部 口腔機能修復学講座 口腔生理学    朝日大学  大学院 歯学研究科    職種   准教授
発表年月日	2026/02/28
発表テーマ	The chorda tympani nerve responses and preferences for different concentration of coffee mixed with thickeners in rats
会議名	The 22th International Symposium on Molecular and Neural mechanisms of Taste and Olfactory Perception (ISMNTOP2025, /YRUF2025, AISCRIB2025)
学会区分	国際学会
発表形式	口頭（一般）
単独共同区分	共同
発表者・共同発表者	Jun Sakai, Chikayo Maeda, Mana Oshio, Shinpei Takahashi, Shusuke Iwata, Toshiaki Yasuo, Takeshi Suwabe, Yoko Iwase, Hiroshige Taniguchi, Noritaka Sako
概要	We investigated whether mixing a thickener with coffee alters chorda tympani nerve responses and preference. Male Wistar/ST rats were used for electrophysiological and behavioral experiments. Whole chorda tympani nerve responses to coffee and bitter stimuli with or without xanthan gum (X; 2.54% or 3.0%) were recorded. In some conditions, responses to mixtures were significantly greater than the arithmetic sum of individual stimuli (p < 0.05), indicating enhancement by X. In a 48-h two-bottle test, rats consumed a mixture of instant coffee (1.7%) and X significantly more than X alone (p < 0.01), despite the bitterness of coffee. These results suggest that xanthan gum enhances both taste nerve responses and preference for coffee in rats.