ヤスオ　トシアキ   YASUO TOSHIAKI   安尾　敏明    所属   朝日大学  歯学部 口腔機能修復学講座 口腔生理学    朝日大学  大学院 歯学研究科    職種   准教授
発表年月日	2026/03/11
発表テーマ	Behavioral response to sodium ascorbate compared with sodium chloride
会議名	The 103rd Annual Meeting of The Physiological Society of Japan
学会区分	全国学会
発表形式	ポスター
単独共同区分	共同
発表者・共同発表者	Toshiaki Yasuo, Shusuke Iwata, Takeshi Suwabe, Shinpei Takahashi, Noritaka Sako
概要	Background: ODS rats lacking ascorbic acid (AsA) synthesis show increased preference and lick responses to AsA and acids. Objective: We examined responses to sodium ascorbate (AsA-Na) and NaCl under AsA-sufficient and -deficient conditions using two-bottle and lick tests. Results: Lick ratios did not differ between AsA-Na and NaCl. At 100 mM, NaCl preference exceeded 80%, whereas AsA-Na remained below 20% (p < 0.01). At 10 mM, AsA-Na preference increased under deficiency and exceeded NaCl (p < 0.05). Lick ratios were generally higher under deficiency, especially at high concentrations. Conclusion: AsA-Na elicits salt-like taste responses, but long-term behavior shows concentration-dependent differences. Post-ingestive effects and AsA status may modulate these responses.