ヤスオ　トシアキ   YASUO TOSHIAKI   安尾　敏明    所属   朝日大学  歯学部 口腔機能修復学講座 口腔生理学    朝日大学  大学院 歯学研究科    職種   講師
発表年月日	2017/11/02
発表テーマ	Detection Of Gut-expressed Jejunal Taste Signaling Elements In Patients With Obesity
会議名	Obesity Week 2017
学会区分	国際学会
単独共同区分	共同
発表者・共同発表者	Toshiaki Yasuo,Peihua Jiang,Craig G Wood,Xin Chu,Peter Benotii,Christropher Still,David D K Rolston
概要	This study aimed to determine if taste signaling is altered in patients with extreme obesity. Methods: The mRNA expression level of PLCb2 and GNAT3 in the proximal discarded jejunum obtained from patients with obesity who underwent bariatric surgery (BMI under 40, 40-49, and 50-59) and was examined using polymerase chain reaction (PCR). Results: Our preliminary data suggest that the intensity of the amplified PLCb2 product from BMI 50-59 patients was lower than those with BMI<50. The intensity of GNAT3 bands was similar across the three BMI groups.