ムカイ　エリコ   MUKAI ERIKO   向井　理英子    所属   朝日大学  歯学部 総合医科学講座 内科学（朝日大学病院）    職種   講師
発表年月日	2018/06
発表テーマ	High-Fat Diet and Constipation
会議名	19th SFRRI Biennial Meeting
学会区分	全国学会
単独共同区分	共同
発表者・共同発表者	Rieko Mukai,Osamu Handa,Shun Takayama,Yousuke Suyama,Atsushi Mttima,ushiroda Chihiro,Hirai Yasuko,Katsura Mizushima,Tetsuya Okayama,Kazuhiro Katada,Kazuhiro Kamada,Kazuhiko Uchiyama,Takeshi lshikawa,Tomohisa Takagi,Yuji Naito
概要	To investigate whether HFD causes constlpation and clarl,the mechanism behind this phenomenon,focusing on the involvement of oxidative stress,male C57BL/6 mice were randomly divided into two groups; feeding HFD and normal diet.Fecal penet numbers,fecal pellet water content and colon transit tilne ttrere measured to evaluate whethe mice are in the state of constipation Colonic malondialdehyde(MDA) density was measured as oxidative stress marker.Compared to mice feeding normal diet,fecal penet numbers、vere less,colon transit tilne was longer,and the MDA density was higher in HFD feeding mice.